Question

In a gene knockout experiment, a lineage of mice was created that lacked uncoupling protein 1 (UCP1), which

enables non-shivering thermogenesis in brown fat by...
a. uncoupling oxidative phosphorylation and ATP production.
b. uncoupling glycolysis and the citric acid cycle.
c. reducing heat production that results from muscle contraction.
d. uncoupling lipogenesis and ATP production.
e. reducing heat lost during cellular respiration.

Answer 1

a. uncoupling oxidative phosphorylation and ATP production. Uncoupling protein 1 (UCP1) enables non-shivering thermogenesis in brown fat by uncoupling oxidative phosphorylation and ATP production.

Step-by-step explanation:

Uncoupling protein 1 (UCP1) enables non-shivering thermogenesis in brown fat by uncoupling oxidative phosphorylation and ATP production. By doing so, it allows the energy to be dissipated as heat instead of being used for ATP synthesis. This process helps generate more heat to maintain body temperature in cold environments.