Question

What process involves the addition or removal of nucleotides when the ends of V, (D), and/or J gene segments are exposed during DNA rearrangement in B cells?

a) Junctional diversity.
b) Allelic exclusion.
c) Isotype switching.
d) Somatic hypermutation.
e) Crossover between maternal and paternal alleles.

Answer 1

Junctional diversity is the process that involves the addition or removal of nucleotides when the ends of V, (D), and/or J gene segments are exposed during DNA rearrangement in B cells.

Step-by-step explanation:

The process that involves the addition or removal of nucleotides when the ends of V, (D), and/or J gene segments are exposed during DNA rearrangement in B cells is called Junctional diversity. Junctional diversity refers to the variability created by the random addition or deletion of nucleotides at the junctions between gene segments. This process generates additional diversity in the antibody repertoire.