Question

Beta cells are for endogenous insulin release. They are functional at start of DM II, but will eventually die if DM II not controlled. True or False.

Answer 1

Beta cells release insulin, and in DM II, they can fail over time if the disease is not controlled, leading to worsened hyperglycemia and contributing to the progression of the disease.

Step-by-step explanation:

The statement that beta cells are responsible for the release of endogenous insulin is true. In Type 2 Diabetes Mellitus (DM II), beta cells are functional at the start but may eventually die if the condition is not well-managed. Over time, chronically high blood glucose levels in DM II can lead to beta cell exhaustion and apoptosis, leading to decreased insulin production and exacerbating the hyperglycemia that is characteristic of DM II. This represents a state of homeostatic imbalance contributing to the disease progression.