Question

Which of the following statements is false?

1) Anti-D is mostly IgG
2) Anti-D can cause HDFN
3) Anti-D usually stimulates complement
4) None of the above

Answer 1

The false statement is that Anti-D usually stimulates complement.

Step-by-step explanation:

The false statement in this question is option 3) Anti-D usually stimulates complement. Anti-D antibodies for the Rhesus system, also known as Rh antibodies, are predominantly of the IgG class, not IgM. They can cause hemolytic disease of the newborn (HDFN) if a woman with Rh- blood type is sensitized to Rh+ blood during pregnancy. However, they do not usually stimulate complement. Instead, they bind and inactivate fetal Rh antigens before they stimulate an immune response in the mother.