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Carbapenems are easily inactivated by the extended-spectrum β-lactamases (ESBLs) produced by certain Gram-negative bacteria so cannot be used to treat these infections.True or False?

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User Hexwab
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Final answer:

Carbapenems are not easily inactivated by ESBLs produced by certain Gram-negative bacteria, so they can be used to treat these infections.

Step-by-step explanation:

False. Carbapenems are not easily inactivated by the extended-spectrum β-lactamases (ESBLs) produced by certain Gram-negative bacteria. ESBLs provide resistance to all penicillins, cephalosporins, monobactams, and ß-lactamase-inhibitor combinations, but not carbapenems.

The carbapenems are a group of drugs that provide very broad-spectrum activity against both gram-positive and gram-negative bacterial pathogens and are often used to treat infections caused by ESBL-producing bacteria.

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User Janne Tuukkanen
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