Question

The mechanism of action of phenothiazine antipsychotics involves ___________.

a. potentiation of norepinephrine and serotonin activity by blocking their reuptake
b. increasing the concentrations of serotonin, norepinephrine, and dopamine by monoamine oxidase enzyme inhibition
c. selective blockade of serotonin reabsorption
d. dopamine receptor blockade

Answer 1

The mechanism of action of phenothiazine antipsychotics involves dopamine receptor blockade.

Step-by-step explanation:

The mechanism of action of phenothiazine antipsychotics involves dopamine receptor blockade. These drugs are antagonists for dopamine, meaning they block dopamine's effects by binding its receptors without activating them. This prevents dopamine released by one neuron from signaling information to adjacent neurons.