Final answer:
To provide adequate anaerobic coverage when using Ceftazidime/Avibactam or Ceftolozane/Tazobactam, an additional antibiotic that is effective against anaerobic bacteria must be given. Examples of such antibiotics include metronidazole or clindamycin.
Step-by-step explanation:
An additional antibiotic that is effective against anaerobic bacteria must be administered with Ceftazidime/Avibactam or Ceftolozane/Tazobactam in order to provide sufficient anaerobic coverage. Metronidazole or clindamycin are two examples of antibiotics that can be used in conjunction with Ceftazidime/Avibactam or Ceftolozane/Tazobactam for anaerobic coverage. Since anaerobic bacteria cannot survive in the presence of oxygen, these antibiotics specifically target and destroy them. A greater variety of bacteria can be efficiently treated by combining the anaerobic coverage of metronidazole or clindamycin with the broad-spectrum activity of ceftazidime/Avibactam or ceftolozane/Tazobactam.