Final answer:
The determination of whether an Ig is secreted or membrane-bound is determined during somatic hypermutation. During somatic hypermutation, B cells undergo random point mutations in the variable region of the Ig gene, which can lead to changes in the structure and function of the Ig.
Step-by-step explanation:
The determination of whether an Ig (immunoglobulin) is secreted or membrane-bound is determined during somatic hypermutation. During somatic hypermutation, B cells undergo random point mutations in the variable region of the Ig gene, which can lead to changes in the structure and function of the Ig. These mutations can affect the signal peptide sequence that directs the Ig to be secreted or remain membrane-bound.
The determination of whether an Ig is secreted or membrane-bound is determined during somatic hypermutation. During somatic hypermutation, B cells undergo random point mutations in the variable region of the Ig gene, which can lead to changes in the structure and function of the Ig.