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Which phases of mitosis are the most difficult to distinguish? Why?

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Answer:

Since prophase and prometaphase are difficult to distinguish; classify the cells as prophase

DNA is the most difficult to visualize at prophase stage of mitosis.

Explaination: At prophase stage,no well defined chromosomes are present. DNA is present in the form of thin chromatin fibers that are difficult to visualize under microscope.

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User Leandros
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