Question

the transfer of complex carbohydrate from dolichol to NXT motif on protein during synthesis trimming of carbohydrate by ER resident glycosyl processing enzymes

Answer 1

The transfer of complex carbohydrates from dolichol to the NXT motif on a protein occurs during the synthesis trimming of carbohydrates by ER resident glycosyl processing enzymes.

Step-by-step explanation:

The transfer of complex carbohydrates from dolichol to the NXT motif on a protein occurs during the synthesis trimming of carbohydrates by ER resident glycosyl processing enzymes. Dolichol is a lipid molecule found in the endoplasmic reticulum (ER), and it serves as a carrier for complex carbohydrates. NXT motif refers to a specific amino acid sequence on a protein that is recognized by the transferase enzymes involved in glycosylation.

During the synthesis of glycoproteins, the ER resident glycosyl processing enzymes trim the carbohydrate chains attached to the protein and transfer complex carbohydrates from dolichol to the NXT motif. This process helps in the proper folding and maturation of glycoproteins. Ultimately, these glycoproteins are transported to their functional locations in the cell, such as the cell surface or other organelles.