Question

What is the purpose of the RAG-1 and RAG-2 and also HMG proteins?

a) Initiate transcription
b) Facilitate splicing
c) Mediate V(D)J recombination
d) Inhibit translation

Answer 1

The purpose of RAG-1 and RAG-2 proteins is to mediate V(D)J recombination. HMG proteins assist in regulating gene expression by facilitating transcription initiation.

Step-by-step explanation:

The purpose of RAG-1 and RAG-2 proteins is to mediate V(D)J recombination. This process involves rearranging DNA segments to create a diverse repertoire of antigen receptors in immune cells. The RAG proteins recognize specific DNA sequences and facilitate the recombination of gene segments that encode the variable regions of antibodies and T-cell receptors. HMG proteins, on the other hand, play a role in DNA bending and protein-DNA interactions. They assist in regulating gene expression by facilitating transcription initiation and promoting the formation of transcription initiation complexes.