Question

Which disorders have been linked with Copy Number Variations (CNVs)?

a) Cystic fibrosis, Marfan syndrome
b) Down syndrome, Turner syndrome
c) Autism spectrum disorder, Schizophrenia
d) Parkinson's disease, Alzheimer's disease

Answer 1

Certain disorders linked to CNVs include Down syndrome, autism spectrum disorder, and schizophrenia.

Step-by-step explanation:

Certain disorders have been linked with Copy Number Variations (CNVs) including:

1. Down syndrome: Down syndrome is caused by having three copies of chromosome 21, also known as trisomy 21. It causes intellectual disability and physical abnormalities.
2. Autism spectrum disorder: CNVs have been implicated in the development of autism spectrum disorder, a neurodevelopmental disorder characterized by impaired social interaction and communication.
3. Schizophrenia: CNVs have also been associated with an increased risk of developing schizophrenia, a mental disorder characterized by delusions, hallucinations, and disorganized thinking.