Final answer:
In ancient times, the Middle East was attacked by the Persians and Mongols, along with some interactions and conflicts with the Romans and Greeks.
Step-by-step explanation:
In ancient times, the Middle East was subjected to attacks from outside by several different empires. These include the Persians, who at their height controlled all of the Middle East including Egypt, and the Mongols, who launched invasions and conquered parts of the region. The Romans and Greeks also had interactions and conflicts with the Middle East, although their influence was not as significant or extensive as that of the Persians and Mongols.