Question

Which of the following is not a role of molecular chaperonins?

1) prevent accidental, premature, or incorrect folding of polypeptide chains
2) aid the desired folding and association process of polypeptides
3) help to translocate proteins and certain metal ions across cell membranes
4) promote the breakdown of damaged or denatured proteins
5) act as a biological catalyst

Answer 1

Molecular chaperonins aid in protein folding and prevent incorrect folding, but they do not promote the breakdown of proteins or act as biological catalysts.

Step-by-step explanation:

The role of molecular chaperonins in cell biology is to assist in the proper folding of proteins. They play several important roles, including:

1. Preventing accidental, premature, or incorrect folding of polypeptide chains.
2. Aiding the desired folding and association process of polypeptides.
3. Helping to translocate proteins and certain metal ions across cell membranes.

However, the role that is not associated with molecular chaperonins is promoting the breakdown of damaged or denatured proteins. This is typically a function of proteases. Moreover, chaperonins do not act as a biological catalyst, which is a role fulfilled by enzymes. Instead, chaperonins aid in the folding process, which is essential for the protein's functionality, particularly under stress conditions such as abnormal temperature or pH.