Question

Which of the following is associated with the docking of mRNA on a ribosome in eukaryotic cells?

a) Shine-Dalgarno sequence
b) Initiator tRNA
c) Kozak sequence
d) Poly-A tail

Answer 1

The docking of mRNA on a ribosome in eukaryotic cells is associated with the Kozak sequence.

Step-by-step explanation:

In eukaryotic cells, the docking of mRNA on a ribosome is associated with the cap-binding protein (CBP) and several other initiation factors (IFs) assisting the movement of the ribosome to the 5' cap. The initiation complex tracks along the mRNA in the 5' to 3' direction, searching for the AUG start codon. Kozak's rules, which indicate the consensus sequence around the AUG, determine the efficiency of translation. Therefore, the correct option is c) Kozak sequence.