asked 69.9k views
5 votes
Reversal agent for neuromuscular blockade in pregnant women:

a) Neostigmine
b) Sugammadex
c) Rocuronium
d) Edrophonium

asked
User FlowRaja
by
7.3k points

1 Answer

5 votes

Final answer:

neostigmine is the traditional reversal agent for neuromuscular blockade in pregnant women, but sugammadex is a newer alternative that encapsulates the neuromuscular blocker molecule, rocuronium.

Step-by-step explanation:

The reversal agent for neuromuscular blockade in pregnant women is neostigmine. This is because it has been used traditionally and is effective for reversing non-depolarizing neuromuscular blockers such as rocuronium and vecuronium. However, it's important to note that sugammadex, a newer agent which acts by encapsulating the steroidal neuromuscular blocker molecule, rocuronium, making it unavailable to bind to the neuromuscular junction, can be considered as an alternative.

While sugammadex is not contraindicated in pregnancy, the benefits versus risks must always be evaluated by a healthcare professional. On the other hand, rocuronium is a neuromuscular blocker itself and not a reversal agent. And edrophonium is an older and less frequently used acetylcholinesterase inhibitor reversible agent with a short duration of action.

answered
User Chrisandra
by
8.2k points
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