Question

Extra credit. An emerging strain of the fungus Candida (C. auris) is able to cause serious infections in humans because it overexpresses a heat shock (chaperone) protein. Most Candida species do not grow well at body temperature and don't cause serious disease. Can you think of some ways that the overexpression of this heat shock protein allows this fungus to cause deadly infections

Answer 1

The correct answer is - explained below.

Step-by-step explanation:

Heat shock proteins can help the protein to get back its natural or native form from the misfolded form and if not possible then degrade it, Therefore it is evident that fungi can grow in stress conditions such as heat in the host's environment with help of such overexpressed chaperons which refolds the protein affected in the process.

C. Auris most of the time does not respond to frequently used antifungals, due to overexpressed chaperons.