Final answer:
The statement is true; George quickly knows Lennie is responsible for the death due to his understanding of Lennie's behavior.
Step-by-step explanation:
The statement George knows immediately that Lennie is responsible for Curley's wife's death is True. In John Steinbeck's novel Of Mice and Men, George's understanding of Lennie's behavior and capability of harm leads him to this quick realization.
George has known Lennie for a long time and is well aware of his strength and the dangers that lie with his actions, especially when under stress or confusion.
The relationship between George and Lennie is built in a way that makes George very perceptive of Lennie's potential actions.