Question

On the basis of "Socransky's Modifications of Koch's Postulates", the potential pathogens in periodontal disease must possess all of the following EXCEPT?

1) be associated with disease, as evidenced by increases in the number of organisms at diseased sites
2) be eliminated or decreased in sites that demonstrate clinical resolution of disease with treatment
3) demonstrate a host response, in the form of alteration in the host cellular, not humeral, immune response
4) be capable of causing disease in experimental animal models
5) demonstrate virulence factors responsible for enabling the organisms to cause periodontal tissue destruction

Answer 1

According to Socransky's modifications of Koch's postulates, the potential pathogens in periodontal disease must possess all of the listed characteristics except for the second statement: they should not be eliminated or decreased in sites that demonstrate clinical resolution of disease with treatment.2) be eliminated or decreased in sites that demonstrate clinical resolution of disease with treatment

Step-by-step explanation:

Koch's postulates are used to determine whether a particular microorganism is a pathogen. According to Socransky's modifications of Koch's postulates, the potential pathogens in periodontal disease must possess all of the following EXCEPT:

1. Be associated with disease, as evidenced by increases in the number of organisms at diseased sites.
2. Be eliminated or decreased in sites that demonstrate clinical resolution of disease with treatment.
3. Demonstrate a host response, in the form of alteration in the host cellular, not humoral, immune response.
4. Be capable of causing disease in experimental animal models.
5. Demonstrate virulence factors responsible for enabling the organisms to cause periodontal tissue destruction.

Based on these criteria, the potential pathogens in periodontal disease must possess all of the listed characteristics except for the second statement: they should not be eliminated or decreased in sites that demonstrate clinical resolution of disease with treatment. This means that even after the disease is treated and resolves, the potential pathogens may still be present in the affected sites.