Question

What are the factors that cause adhesion of platelets to the sub endothelial matrix?

1) Platelet activation
2) Exposure of collagen
3) Release of von Willebrand factor
4) All of the above

Answer 1

The factors that cause platelets to adhere to the sub endothelial matrix are platelet activation, exposure of collagen, and release of von Willebrand factor. All of these factors contribute to the formation of a platelet plug.

Step-by-step explanation:

The factors that cause adhesion of platelets to the sub endothelial matrix are platelet activation, exposure of collagen, and release of von Willebrand factor. When platelets encounter an area of vessel rupture with exposed collagen and connective tissue, they clump together, become spiked and sticky, and bind to the exposed collagen and endothelial lining. This process is assisted by von Willebrand factor, which helps stabilize the growing platelet plug. Therefore, the correct answer is option 4) All of the above.