Final answer:
For the treatment of acne vulgaris with closed comedones, benzoyl peroxide is often the primary initial treatment. It's available over-the-counter and works by reducing bacteria and inflammation.
Step-by-step explanation:
The primary initial treatment for acne vulgaris with closed comedones is often a topical agent, particularly benzoyl peroxide.
This treatment is recommended because it works by killing bacteria, reducing inflammation, and helping to prevent the formation of new acne lesions. Mild acne, such as the presence of closed comedones, generally responds well to benzoyl peroxide or salicylic acid, both of which are available over-the-counter.
For more persistent cases, a visit to a dermatologist is advisable as they may prescribe additional medications or suggest other treatments such as laser light therapies or chemical peels.