Final answer:
The major apolipoprotein associated with chylomicrons is apolipoprotein B-48, and it is synthesized in the small intestine.
Step-by-step explanation:
The major apolipoprotein associated with chylomicrons and their place of synthesis can be answered with an understanding of lipid metabolism.
Chylomicrons are lipoprotein particles that primarily transport dietary lipids from the intestines to other parts of the body. The main apolipoprotein component of chylomicrons is apolipoprotein B-48 (apo B-48), which is essential for the assembly and secretion of chylomicrons. Apo B-48 is synthesized in the small intestine, which is the site where chylomicrons are also formed. As such, the correct answer to the question is: a) Apolipoprotein B-48; Small Intestine.