Question

Which enzyme is responsible for regulating cholesterol esterification and promoting cholesterol ester storage?

a) Lipoprotein Lipase
b) Acyl-CoA Synthetase
c) Lecithin-Cholesterol Acyltransferase (LCAT)
d) Hormone-Sensitive Lipase (HSL)

Answer 1

Lecithin-Cholesterol Acyltransferase (LCAT) is the enzyme responsible for regulating cholesterol esterification and promoting cholesterol ester storage.

Step-by-step explanation:

The enzyme responsible for regulating cholesterol esterification and promoting cholesterol ester storage is Lecithin-Cholesterol Acyltransferase (LCAT).

LCAT transfers a fatty acid from lecithin to cholesterol to form the cholesterol ester. Cholesterol esters are important for the storage and transport of cholesterol in lipoproteins, particularly in high density lipoproteins (HDL). HDL transports cholesterol from tissues to the liver, preventing atherosclerosis.