Final answer:
The first publishing house was built in Venice, which became the printing capital of Europe by 1480.
Step-by-step explanation:
The first publishing house was built in Venice, making the correct answer to the question D) Venice. Gutenberg's printing press, although not the first method of producing print media, revolutionized the way information was spread, making the distribution of knowledge more efficient. Consequently, Venice became the printing capital of Europe by 1480, with early printers there designing fonts similar to those we use today. This innovation in the dissemination of text contributed significantly to periods such as the Renaissance and the Age of Enlightenment.