Final answer:
In a liver lobule, blood enters the sinusoids from the hepatic artery and the hepatic portal vein and exits through the central vein to the hepatic veins and into the inferior vena cava.
Step-by-step explanation:
In a liver lobule, blood flows within sinusoids from branches of the hepatic artery and hepatic portal vein to the central vein. The hepatic artery provides oxygen-rich blood from systemic circulation, while the hepatic portal vein delivers nutrient-rich blood from the gastrointestinal tract. Hepatic sinusoids facilitate the transfer of substances between the blood and the liver cells, or hepatocytes. These hepatocytes are responsible for processing nutrients, detoxifying substances, and producing bile. After passing through the sinusoids, the blood combines and exits the liver through the hepatic veins, eventually flowing into the inferior vena cava.