Final answer:
The cell membrane allows communication between an extracellular compartment and the interior of a cell by controlling what enters and exits the cell.
Step-by-step explanation:
Communication between an extracellular compartment and the interior of a cell is made possible by the cell membrane of the cell. The cell membrane acts as a selective barrier, controlling the passage of organic molecules, ions, water, oxygen, and wastes into and out of the cell. It operates through various mechanisms including simple diffusion, facilitated transport, and active transport, ensuring the proper exchange of matter necessary for the cell's functions.