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A rare situation where only one of the two copies of a particular tumor-suppressor gene needs to be inactivated before there is a progression toward cancer is called:__________

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Final answer:

The rare situation where only one of the two copies of a tumor-suppressor gene needs to be inactivated before there is a progression toward cancer is called dominant negative effect.

Step-by-step explanation:

The rare situation where only one of the two copies of a tumor-suppressor gene needs to be inactivated before there is a progression toward cancer is called dominant negative effect.

Normally, tumor suppressor genes act as a brake pedal in the cell's cycle, preventing uncontrolled division. However, in some cases, one mutated allele of a tumor suppressor gene can render the other copy non-functional, leading to unwanted cell division and cancer progression.

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