Question

Elevated alk phos, normal transaminases, normal RUQ US, and positive antimitochondrial antibody assay? Tx?

a) Primary biliary cholangitis (PBC); Ursodeoxycholic acid (UDCA)
b) Acute hepatitis; Antivirals
c) Gallstones; Cholecystectomy
d) Cirrhosis; Liver transplantation

Answer 1

Elevated alk phos, normal transaminases, normal RUQ US, and positive antimitochondrial antibody assay likely indicates primary biliary cholangitis (PBC). The recommended treatment for PBC is ursodeoxycholic acid (UDCA).

Step-by-step explanation:

The elevation of alkaline phosphatase (alk phos) along with normal transaminases (AST/ALT) and normal RUQ US (right upper quadrant ultrasound) can indicate a condition known as primary biliary cholangitis (PBC). This condition involves inflammation and destruction of the small bile ducts in the liver.

The positive antimitochondrial antibody assay confirms the diagnosis of PBC. The recommended treatment for PBC is ursodeoxycholic acid (UDCA), which helps to improve liver function and slow down disease progression.