Final answer:
Hormonal changes during menopause result in decreased estrogen production, leading to menopause symptoms and contributing to conditions such as atrophic dermatosis due to skin changes. Lowered estrogen levels can also lead to systemic conditions like osteoporosis.
Step-by-step explanation:
As a woman approaches the age of menopause, hormonal changes lead to the depletion of ovarian follicles, significantly affecting the menstrual cycle. The decrease in the hormone inhibin stimulates the production of FSH, which then causes more follicles to grow and secrete estrogen. However, since most of these follicles undergo atresia and die, this leads to a decline in estrogen production. The lack of estrogens, as a result, leads to classic symptoms of menopause, such as hot flashes, night sweats, and mood swings.
In the context of atrophic dermatosis, the reduced estrogen levels resulting from menopause can contribute to skin elasticity issues and slower wound healing. This is due to decreased mitosis in the stratum basale of the skin, a thinner epidermis, and a dermis with reduced regenerative ability. Lowered estrogen levels can also lead to systemic conditions like osteoporosis, atherosclerosis, and hyperlipidemia.