Question

Amphotericin B

A) disruption of cytoplasmic membranes
B) inhibitio of cell wall synthesis
C) inhibition of nucleic acid synthesis
D) inhibition of metabolic pathways
E) inhibition of protein synthesis

Answer 1

Amphotericin B disrupts the cytoplasmic membranes of fungi by targeting the synthesis of ergosterol, a sterol found in fungal cell membranes but not in human cells.

Step-by-step explanation:

Amphotericin B is an antifungal drug that disrupts the cell membrane of fungi. It targets the synthesis of ergosterol, a sterol found in fungal cell membranes but not in human cells. By interfering with ergosterol synthesis, Amphotericin B selectively damages fungal cell membranes, making it toxic to fungi.

Therefore, the correct answer is A) disruption of cytoplasmic membranes.