Question

Which of the following phenotypes is found in people with mutations in cystic fibrosis transmembrane conductance regulator (CFTR)?

A Cystic fibrosis
B Congenital bilateral absence of the vas deferens
C Idiopathic chronic pancreatitis
D Meconium ileus
E Any or all of the above

Answer 1

Mutations in the CFTR gene result in various phenotypes including cystic fibrosis, congenital bilateral absence of the vas deferens, idiopathic chronic pancreatitis, meconium ileus, and potentially any combination of these.

Step-by-step explanation:

The phenotypes found in people with mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) include A) Cystic fibrosis, B) Congenital bilateral absence of the vas deferens, C) Idiopathic chronic pancreatitis, D) Meconium ileus, and E) Any or all of the above. Mutations in the CFTR gene cause defective proteins that result in thick and sticky mucus, which can block organs and lead to various symptoms.