Question

Which of the following is true ONLY for association studies, as compared to linkage studies?

A Can use thousands of markers in the analysis
B Can identify the functional risk allele for the trait of interest
C Families can be used in the analysis
D Makes use of the correlation between recombination and genetic distance
E Requires model specification

Answer 1

The correct answer is A) Can use thousands of markers in the analysis.

Step-by-step explanation:

The correct answer to the question is A) Can use thousands of markers in the analysis. This statement is true only for association studies, as compared to linkage studies.

Association studies, also known as genome-wide association studies (GWAS), identify differences between individuals in single nucleotide polymorphisms (SNPs) that may be involved in causing diseases. These studies can use thousands of markers (SNPs) in the analysis to capture the genomic variation across the population. By analyzing these markers, GWAS can identify genetic associations with diseases or traits.

In contrast, linkage studies analyze the recombination frequency between genes to determine if they are linked or show independent assortment. Linkage studies do not typically use thousands of markers in the analysis.