Question

What are the physiologic and pharmacologic effects of estrogen and progesterone in premenopausal women that contribute to a favorable impact on lipid metabolism?

Option 1: Estrogen and progesterone decrease HDL and increase LDL levels, leading to a negative effect on lipid metabolism.

Option 2: Estrogen and progesterone have no significant impact on lipid metabolism in premenopausal women.

Option 3: Estrogen and progesterone increase HDL levels and decrease LDL levels, contributing to a favorable effect on lipid metabolism.

Option 4: Estrogen and progesterone inhibit cholesterol secretion, resulting in an unfavorable effect on lipid metabolism in premenopausal women.

Answer 1

Estrogen and progesterone have a favorable impact on lipid metabolism in premenopausal women. They increase HDL levels and decrease LDL levels, which helps prevent cardiovascular diseases.

Step-by-step explanation:

Estrogen and progesterone have a favorable impact on lipid metabolism in premenopausal women. They increase HDL (high-density lipoprotein) levels and decrease LDL (low-density lipoprotein) levels. Higher levels of HDL help remove LDL from the arteries, preventing the build-up of plaque and reducing the risk of cardiovascular disease. This positive effect on lipid metabolism contributes to better overall cardiovascular health.