Question

Which of the following is a first-line anti-tubercular drug and serves as a prototype for this class?

Options:

Rifampicin
Ethambutol
Isoniazid (INH)
Pyrazinamide

Answer 1

Isoniazid (INH) is a first-line anti-tubercular drug and serves as a prototype for this class.

Step-by-step explanation:

Isoniazid (INH) is a first-line anti-tubercular drug and serves as a prototype for this class. It is administered as a prodrug and inhibits the synthesis of mycolic acid, which is essential for mycobacterial cell walls. Common side effects of isoniazid use include hepatotoxicity, neurotoxicity, and hematologic toxicity.