Final answer:
Naïve B and T cells are resting lymphocytes that have not engaged in an immune response, as they have not yet encountered pathogenic antigens.
Step-by-step explanation:
Naïve or small lymphocytes are resting cells that have not engaged in immune response. These cells, namely naïve B and T cells, are part of the adaptive immune system and circulate in the body without having encountered pathogenic antigens. Activated B cells differentiate and produce antibodies as part of the humoral immune response, while activated T cells stimulate the cell-mediated immune response. Naïve lymphocytes become effector cells when they encounter an antigen and are activated.