Question

Following testing for lipid levels, the results for a 28-year-old male are consistent with the diagnosis of type I hyperlipoproteinemia. Which of the following is the most likely consequence of this condition?

A) Glomerulonephritis
B) Cholecystitis
C) Coronary vascular disease
D) Pancreatitis

Answer 1

For a 28-year-old male diagnosed with type I hyperlipoproteinemia, the most likely consequence is pancreatitis. This is due to the elevated chylomicrons leading to acute inflammation of the pancreas.

Step-by-step explanation:

Hyperlipoproteinemia type I, also known for its rarity and association with elevated chylomicrons due to a deficiency in lipoprotein lipase (LPL) or altered apolipoprotein C2, predisposes individuals to pancreatitis. This condition leads to improper breakdown of fats and an accumulation of fatty particles in the blood, which can have various health consequences. Among the potential consequences listed, pancreatitis is the most likely to occur because the elevated levels of chylomicrons can cause an acute inflammation of the pancreas. In contrast, glomerulonephritis, cholecystitis, and coronary vascular disease are less consistently directly associated with this specific type of hyperlipoproteinemia.