Final answer:
Acetylcholine binds to the nicotinic receptor in the somatic nervous system.
Step-by-step explanation:
The cholinergic system includes two classes of receptor: the nicotinic receptor and the muscarinic receptor. Both receptor types bind to acetylcholine (ACh) and cause changes in the target cell. The nicotinic receptor is a ligand-gated cation channel, while the muscarinic receptor is a G protein-coupled receptor. Nicotine, which is named after the nicotinic receptor, will bind to the nicotinic receptor, but not to the muscarinic receptor.