Final answer:
The most significant complication associated with oropharyngeal suction is hypoxia due to prolonged section attempts.
Step-by-step explanation:
The MOST significant complication associated with oropharyngeal section is hypoxia due to prolonged section attempts. When performing suctioning in the oropharynx, there is a risk of prolonged suction attempts resulting in reduced oxygen delivery to the body. This can lead to hypoxia, which is a condition where the body tissues do not receive enough oxygen.