Question

The sample size in a phase Ill study is driven by the number of deaths expected. Of the following, which scenario would require the largest number of patients?

Answer 1

In a phase III study, the sample size is determined by the number of deaths expected. The scenario with the highest expected number of deaths would require the largest number of patients.

Step-by-step explanation:

In a phase III study, the sample size is driven by the number of deaths expected. The scenario that would require the largest number of patients is the one with the highest expected number of deaths. This is because a larger sample size is needed to ensure that the results are statistically significant.