Question

During the intestinal phase of gastric regulation, __________.

A. the gastroenteric reflex reduces stomach activity
B. secretin causes more HCl release
C. hormones reduce chief cell activity
D. the enterogastric reflex is turned off
E. the stomach is initially stimulated and later inhibited

Answer 1

During the intestinal phase of gastric regulation, the stomach is initially stimulated and later inhibited. Intestinal mucosal cells release intestinal gastrin, which further stimulates gastric juice secretion. However, when the intestine distends with chyme, the enterogastric reflex inhibits secretion. Therefore, the most appropriate correct option is E.

Step-by-step explanation:

During the intestinal phase of gastric regulation, the stomach is initially stimulated and later inhibited. When partially digested food fills the duodenum, intestinal mucosal cells release a hormone called intestinal (enteric) gastrin, which further excites gastric juice secretion. However, when the intestine distends with chyme, the enterogastric reflex inhibits secretion, closing the pyloric sphincter to block additional chyme from entering the duodenum.