Final answer:
The relative frequencies of genotypes differ between South Carolina and West Africa due to genetic variation and historical factors.
Step-by-step explanation:
The relative frequencies of genotypes in South Carolina and West Africa differ due to genetic variation and historical factors. In South Carolina, the genetic variation is influenced by the importation of Africans during the slave trade, leading to a diverse gene pool. On the other hand, West Africa has a wider genetic variation due to a larger number of ethnic groups and longer human habitation. This has resulted in a greater diversity of genotypes and alleles.