Question

Which gene mutation(s) are associated with an increased risk of breast CA?

Answer 1

The gene mutations associated with an increased risk of breast cancer are the BRCA1 and BRCA2 mutations. These mutations greatly increase the risk of breast and ovarian cancer in women.

Step-by-step explanation:

The gene mutations associated with an increased risk of breast cancer are the BRCA1 and BRCA2 mutations. These mutations greatly increase the risk of breast and ovarian cancer in women.

For example, women with a harmful mutation in the BRCA1 gene have a 55 to 65% chance of developing breast cancer before age 70, compared to only 12% of women in the general population.

In addition to the BRCA genes, mutations in the gene for the p53 protein (TP53) are also associated with an increased risk of breast cancer