Question

What are the possible modifications that can occur in a protein?

1) Phosphorylation (P)
2) Acetylation (A)
3) Both phosphorylation and acetylation
4) Neither phosphorylation nor acetylation

Answer 1

Proteins can undergo phosphorylation and acetylation, which can affect their function, activity, stability, and localization. Phosphorylation can regulate gene expression through various mechanisms, while acetylation can impact protein activity and longevity.

Step-by-step explanation:

Proteins can undergo various modifications after translation, including phosphorylation and acetylation. Phosphorylation involves the addition of a phosphate group to specific amino acid residues in the protein, while acetylation involves the addition of an acetyl group. These modifications can alter the function, activity, stability, and localization of the protein. Phosphorylation, for example, can regulate gene expression by affecting translation, RNA shuttling, RNA stability, or post-transcriptional modification. Acetylation can also impact gene expression by regulating protein activity or longevity.