Question

The cystic fibrosis transmembrane regulator (CFTR) is an ABC transporter that functions as a __________ ion channel.

1) Na⁺
2) Ca++
3) K⁺
4) Cl⁻

Answer 1

The cystic fibrosis transmembrane regulator (CFTR) is an ABC transporter that functions as a Cl⁻ ion channel in both healthy individuals and individuals with cystic fibrosis (CF).

Step-by-step explanation:

The cystic fibrosis transmembrane regulator (CFTR) is an ABC transporter that functions as a Cl⁻ ion channel.

In healthy people, the CFTR protein transports Cl- ions out of the cell. However, in individuals with cystic fibrosis (CF), the mutated CFTR gene produces a defective channel protein that is not incorporated into the membrane.

The CFTR requires ATP to function, allowing the transport of Cl- ions out of the cell. This form of transport is considered active transport, as the Cl- ions are flowing down their concentration gradient.