Final answer:
The signal peptide binds to a hydrophobic site on the ribosome, causing a pause in protein synthesis. The SRP binds to the signal peptide and helps guide the ribosome to the ER membrane.
Step-by-step explanation:
The subject of this question is Biology.
When a signal peptide binds to a hydrophobic site on the ribosome, it causes a pause in protein synthesis.
This pause allows for the recognition of the signal peptide by the signal recognition particle (SRP), which binds to the signal peptide and helps guide the ribosome to the endoplasmic reticulum (ER) membrane.
Once the ribosome-SRP complex binds to an SRP receptor on the ER membrane, protein synthesis resumes.