Final answer:
Before the Columbian Exchange, pigs were never seen in Europe.
Step-by-step explanation:
The correct option that was never seen in Europe before the Columbian Exchange is D) Pigs.
Pigs were unknown in the Americas before Hernán do de Soto brought them to the Florida mainland.
Columbus also brought red pigs to the Americas on his second voyage.
They were later brought into the United States from the Guinea coast of Africa on early slave-trading vessels.
To summarize, before the Columbian Exchange, Europe had not seen pigs.