Final Answer:
The volume of the largest circular cylinder that can be inscribed in a circular cone with radius 5 inches and height 8 inches is 
 cubic inches.
Step-by-step explanation:
Let's denote:
- 
 as the radius of the cylinder,
- 
 as the height of the cylinder.
The cylinder is inscribed in the cone, so its dimensions must satisfy the conditions of the cone. In particular, the radius of the cylinder 
 must be equal to the radius of the cone's base (5 inches).
The height of the cylinder 
 plus the height of the remaining frustum of the cone must be equal to the height of the cone (8 inches).
Let's express the height of the frustum 
 in terms of 
 using similar triangles:
![\[ (h')/(r) = (8 - h)/(5) \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/8m43uxs4pwfxdhw5ekpsnxkk8z7yn4mv3b.png)
Solving for 

![\[ h' = (r(8 - h))/(5) \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/5i4nqrrge90bqdkzfie9vjqe9kuqy9q2c3.png)
The volume 
 of the cylinder is given by:
![\[ V = \pi r^2 h \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/ug30de7ei4kh0ajv58c9y4n4ti9utw2few.png)
Substituting the expressions for 
 and 

![\[ V = \pi \left(5^2\right) \left((r(8 - h))/(5)\right) \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/vevecwjjws3xx5l46gbdoek6q9mbwt9sau.png)
Simplifying:
![\[ V = (\pi)/(5) r(8 - h)r^2 \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/7aropbwpx18a5flyjgvrjhtlu0iq2rlicy.png)
We know that 
 (radius of the cone), and 
 (height of the cone). Substituting these values:
![\[ V = (\pi)/(5) \cdot 5(8 - h) \cdot 5^2 \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/wrsdwlhm2y5vqexl3auou1gzs3ijg2omhw.png)
Simplifying further:
![\[ V = (320\pi)/(3) \]](https://img.qammunity.org/2024/formulas/mathematics/high-school/v5844ujlt2yhwxs7kb0309t6fiv9royjpb.png)
Therefore, the volume of the largest circular cylinder that can be inscribed in the given circular cone is 
 cubic inches.