Final answer:
In the first few years at the colony of Jamestown, many men died due to factors such as diseases, hunger, conflicts with local natives, and internal disputes. The winter of 1609-1610, known as "the starving time", was especially destructive, resulting in a high death toll.
Step-by-step explanation:
The Jamestown colony faced numerous hardships, resulting in a high death toll in the first few years. Disease, hunger, poor relationships with local natives, bad weather, internal political disputes, and military conflicts all contributed to the high mortality rate. The winter of 1609-1610, known as "the starving time", was particularly devastating, causing the deaths of many colonists. By May 1610, fewer than a hundred colonists remained.