Final answer:
Arterial CO₂ is the primary stimulus for changes in ventilation.
Step-by-step explanation:
The statement "Arterial CO₂ is the primary stimulus for changes in ventilation" is true. Both respiratory rate and depth are controlled by the respiratory centers of the brain, which are stimulated by changes in the levels of carbon dioxide in the blood. When carbon dioxide levels rise, it stimulates an increase in respiratory rate and depth to remove carbon dioxide from the blood.