Question

Which of the following mechanisms describes how eukaryotic activator proteins can regulate chromatin packaging to enhance transcription?

A. binding to enhancer regions to promote formation of the transcription initiation complex

B. activating polymerase binding through contacts made in the activation region

C. recruiting histone deacetylase complexes to remove acetyl groups from histones

D. recruiting chromatin-remodeling complexes to eject or slide nearby nucleosomes

Answer 1

Eukaryotic activator proteins regulate chromatin packaging to enhance transcription by recruiting chromatin-remodeling complexes to eject or slide nearby nucleosomes.

Step-by-step explanation:

Eukaryotic activator proteins can regulate chromatin packaging to enhance transcription by recruiting chromatin-remodeling complexes to eject or slide nearby nucleosomes. These activator proteins can change the conformation of chromatin by altering the positioning of nucleosomes, making the DNA more accessible for transcription. This mechanism allows the activator proteins to promote the binding of transcription factors and RNA polymerase to the DNA, leading to enhanced transcription.